Green Chemistry in Pharmaceutical Industries
Green chemistry is being employed to develop revolutionary drug delivery ways in which area unit additional sensible and fewer toxic and can profit multitudinous patients. Solid-phase synthesis of antisense oligonucleotides has been changed to accommodate principles of inexperienced chemistry by eliminating the employment and generation of toxic materials and allowing employees of valuable materials like amenities, solid-support, and protecting groups, thus raising the atom economy and cost-efficiency.
In the past, the industrial production of Adipic acid used benzene as a starting material. Benzene is one of the basic chemicals for industrial reactions and a solvent. It is known that derives mainly from the refining processes of the petrochemical industry. Benzene is also known for its carcinogenic properties (it causes leukemia to highly exposed workers). Afterwards the starting material became cyclohexanone or a mixture of cyclohexanone and cyclohexanol. For the oxidation process it was used nitric acid, producing toxic fumes of nitric oxides, NOx, which are also contributors to the greenhouse effect and the destruction of the ozone layer in the strat osphere. It was Inevitable that the method had to be changed again with more environmentally benign reactions.