Yehya Kamal Al-Bayati
Baghdad University, Iraq
Title: Synthesis of ibuprofen–molecularly imprinted polymers and used as sensors to determine the drug in pharmaceutical preparations
Biography
Biography: Yehya Kamal Al-Bayati
Abstract
Two molecularly imprinted polymers (MIPs) were prepared by using ibuprofen as the template a well as methacrylic acid (MAA) or acrylamide (ACY) as monomer, used ethylene glycol dimethacrylate (EGDMA) or trimethylol propane triacrylate (TMPTA) as cross linker, and benzoyl peroxide as initiator. NIPs prepared by using the same composition of MIPs except the template (IBP). The membrane of MIPs, NIPs were prepared by using di butyl phthalate (DBPH), oleic acid (OA), paraffin (PRF) and o-nitro phenyloctylether (ONPOE) as plasticizers in PVC matrix. The slope, detection limit, linearity range of electrodes MIPs from (-54.25, -45.23) mV/decade, (1.09×10-6 M-9×10-6 M) and (1×10-5-1×10-1) , respectively, and show stable response in a pH rang from (3.5-7.5) and studied the selectivity with inorganic ions (Na+, Li+, Ca2+, Mg2+, Fe3+ and Al3+ ) show good selectivity .