Subodh Eknathrao Bhandarkar
Government Vidarbha Institute of Science & Humanities, India
Title: Green synthesis, characterization and biological study of Aurane derivatives
Biography
Biography: Subodh Eknathrao Bhandarkar
Abstract
Heterocyclic chemistry is one of the most complex and intriguing branch of organic chemistry and it constitutes the largest and most varied family of organic compounds. Aurones are responsible for the bright yellow color of some popular ornamental flowers suchas snapdragon, cosmos and dahlia Aurones are heterocyclic compound and till date approximately 100 aurones have been reported from natural sources, mainly flowering plants and a few ferns, mosses and marine brown algae. The literature survey reveals that aurone derivatives have been studied extensively because of their broad spectrum of biological activity, variety of Industrial applications and diverse chemical reactivity. Due to this vital biological role of aurone derivatives it was thought to synthesized substituted aurones. 2-acetyl –substituted phenols were prepared by modified Nenchi’s method which on treatment with aromatic aldehydes and KOH gives chalcones in an excellent yield. These chalcones along with aromatic aldehydes in a microwave gives auranes in 56 - 59% yield. Thin Layer Chromatography on silica gel-G, was used to check the purity of the compounds. The synthesized compounds were characterized by elemental analysis, 1H NMR and IR Spectroscopy. All Newly synthesized compound were scanned for their antimicrobial and antifungal activity and all newly synthesized compounds shows an excellent antimicrobial and antifungal activities.