Marion H Emmert
Worcester Polytechnic Institute, USA
Title: Transition Metal Catalysis for Non-Directed C-H Functionalization
Biography
Biography: Marion H Emmert
Abstract
Catalysis is one of the most powerful tools of green chemistry, enabling reactions with lower energy consumption and providing new pathways for bond formation. Catalytic C-H functionalizations, in particular, are powerful methodologies for installing functional groups in previously non-functionalized positions of a molecule and the use of catalyst directing groups has enabled a wide variety of exciting bond formations with remarkable selectivities and broad applicability.One of the greatest current challenges in this research area is how to catalyze analogous C-H functionalization reactivity without the presence of catalyst directing groups. Such transformations often suffer from the lack of a strong catalyst pre-coordination, which can lead to lower reactivities.The research described in this presentation will showcase basic principles of catalyst and methodology design to achieve non-directed C-H functionalizations and provide insights into reactivity and selectivity-determining factors for the C-H aminations of arenes and the alpha-C H oxidation of tertiary amines.
