David Morales-Morales
Instituto de Quimica, Mexico
Title: Suzuki-Miyaura Cross coupling reactions in water. New hydrophilic ligand scaffolds from Pincer compounds to cocoa beans.
Biography
Biography: David Morales-Morales
Abstract
Catalysis is at the core of green chemistry, constituting one of the principles of this doctrine and representing one of its fundamental pillars. Among the most celebrated catalyzed chemical transformations are the cross coupling reactions and one that has had a tremendous development in the last decade is the Suzuki-Miyaura reaction. Being considered nowadays a fundamental power tool in organic synthesis. Recent advances in this area deal with the use of this process in water, using alternative energy sources, employing highly reactive and selective catalyst, preferable soluble in water. Thus, in this work we will present recent developments on the design and synthesis of novel hydrophilic ligand scaffolds including pincer ligands, secondary amines having hydrophilic substituents and naturally occurring compounds such as theophylline and other xanthine derivatives. The results on the use of these ligands in cross coupling reactions in water or aqueous media will be discussed.