J S Yadav
Indian Institute of Chemical Technology, India
Title: Green methods for new chemical entities (NCE’s)
Biography
Biography: J S Yadav
Abstract
Water mediated organic reactions are very useful in view of environmental consciousness. Therefore, organic transformations that are performed in water will be discussed in details. In particular, transition metal catalyzed transformations in the synthesis of heterocycles will be discussed. The use of water tolerant Lewis acids such as indium salts, scandium triflate will be demonstrated for the C-C, C-N and C-S bond formation. In addition, a few indium-mediated transformations like Barbier type allylation reaction of carbonyl compounds, epoxides, acetals, reduction of N-oxides and reductive alkylations of azides which are performed in water will be discussed as they are simple, convenient and environmentally friendly.