Serkan Sayin
Selcuk University, Turkey
Title: Catalytic affinities of magnetic nano-Fe3O4-adorned calix[n]arene
Biography
Biography: Serkan Sayin
Abstract
Not only magnetite properties, but easily also tunable surface modification of iron oxide nanoparticles adorning with diverse core sized have provided them potential applications in many fields such as bioseparation, tumor hyperthermia, Magnetic Resonance Imaging (MRI), diagnostic contrast agents, magnetically guided site-specific drug delivery agents, biomolecules immobilization, and etc. Iron oxide nanoparticles, which have gained more attention on, has been also employed as supports for selectively functionalized calixarene derivatives, which are mostly effective ionophores for several toxic as well as carcinogenic water contaminant anions or cations but unfortunately soluble in water. Due to the water solubility issue, such calixarenes could not have used as an extractant, however, acquiring magnetic properties to calixarenes, the solubility problem was handled as well as separation and reusable processes became an easy task. Besides of their extraction capabilities towards such ions, calix[n]arene-grafted iron oxide nanoparticles have been extensively used in the encapsulation reaction of Candida rugosa lipase in order to enhance the catalytic activity and enantioselectivity of lipases in the hydrolysis reaction of some racemic pro-drugs. The present work is concerned about construction of several magnetically recoverable Brønted acidic calix[n]arene derivatives by adorning calix[n]arene sulfonic acids that substituted with different groups onto silica coated magnetic nanoparticles regarding to provide magnetic properties. In this lecture is shown how the present Brønted acid type calix[n]arene-grafted magnetic nanoparticles are capable, and would be a pioneer as supramolecular acid catalysts in the coupling reaction of electron-rich arenes with some alcohols in water.